7F1V

Crystal structure of Pseudomonas putida methionine gamma-lyase Q349S mutant with L-homocysteine intermediates

Summary for 7F1V

Entry DOI	10.2210/pdb7f1v/pdb
Descriptor	L-methionine gamma-lyase, (2~{S})-2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-4-sulfanyl-butanoic acid, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, ... (5 entities in total)
Functional Keywords	lyase, pseudomonas putida, methionine gamma-lyase, plp enzyme
Biological source	Pseudomonas putida (Arthrobacter siderocapsulatus) More
Total number of polymer chains	4
Total formula weight	171854.34
Authors	Okawa, A.,Handa, H.,Yasuda, E.,Murota, M.,Kudo, D.,Tamura, T.,Shiba, T.,Inagaki, K. (deposition date: 2021-06-09, release date: 2022-04-20, Last modification date: 2024-03-13)
Primary citation	Okawa, A.,Handa, H.,Yasuda, E.,Murota, M.,Kudo, D.,Tamura, T.,Shiba, T.,Inagaki, K. Characterization and application of l-methionine gamma-lyase Q349S mutant enzyme with an enhanced activity toward l-homocysteine. J.Biosci.Bioeng., 133:213-221, 2022 Cited by PubMed: 34953671 DOI: 10.1016/j.jbiosc.2021.11.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation