7EYI
Crystal structure of ZBTB7A in complex with gamma-globin -200 sequence element with C-194A mutation
Summary for 7EYI
Entry DOI | 10.2210/pdb7eyi/pdb |
Descriptor | Zinc finger and BTB domain-containing protein 7A, DNA (5'-D(*AP*TP*AP*GP*GP*GP*CP*CP*CP*CP*TP*TP*CP*CP*CP*AP*AP*C)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*GP*GP*AP*AP*GP*GP*GP*GP*CP*CP*CP*TP*A)-3'), ... (6 entities in total) |
Functional Keywords | zbtb7a, gamma-globin, -200 cluste., structural protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 52876.80 |
Authors | |
Primary citation | Yang, Y.,Ren, R.,Ly, L.C.,Horton, J.R.,Li, F.,Quinlan, K.G.R.,Crossley, M.,Shi, Y.,Cheng, X. Structural basis for human ZBTB7A action at the fetal globin promoter. Cell Rep, 36:109759-109759, 2021 Cited by PubMed: 34592153DOI: 10.1016/j.celrep.2021.109759 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.401 Å) |
Structure validation
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