7EPT

Structural basis for the tethered peptide activation of adhesion GPCRs

7EPT の概要

• エントリーDOI: 10.2210/pdb7ept/pdb
• EMDBエントリー: 31232
• 分子名称: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: adhesion gpcr, gpr133, structural protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 138316.35

構造登録者

Ping, Y.-Q.,Xiao, P.,Yang, F.,Zhao, R.-J.,Guo, S.-C.,Yan, X.,Wu, X.,Liebscher, I.,Xu, H.E.,Sun, J.-P. (登録日: 2021-04-27, 公開日: 2022-05-11)

• 主引用文献: Ping, Y.Q.,Xiao, P.,Yang, F.,Zhao, R.J.,Guo, S.C.,Yan, X.,Wu, X.,Zhang, C.,Lu, Y.,Zhao, F.,Zhou, F.,Xi, Y.T.,Yin, W.,Liu, F.Z.,He, D.F.,Zhang, D.L.,Zhu, Z.L.,Jiang, Y.,Du, L.,Feng, S.Q.,Schoneberg, T.,Liebscher, I.,Xu, H.E.,Sun, J.P.; Structural basis for the tethered peptide activation of adhesion GPCRs.; Nature, 604:763-770, 2022; PubMed: 35418678; DOI: 10.1038/s41586-022-04619-y

実験手法

ELECTRON MICROSCOPY (3 Å)