7ENY

Crystal structure of hydroxysteroid dehydrogenase from Escherichia coli

Summary for 7ENY

• Entry DOI: 10.2210/pdb7eny/pdb
• Descriptor: 7alpha-hydroxysteroid dehydrogenase (2 entities in total)
• Functional Keywords: ketolithocholic acid, alcohol dehydrogenase, hydroxysteroid dehydrogenase, ursodeoxycholic acid, hydrolase
• Biological source: Escherichia coli K-12
• Total number of polymer chains: 8
• Total formula weight: 242563.64

Authors

Kim, K.-H.,Lee, C.W.,Pardhe, D.P.,Hwang, J.,Do, H.,Lee, Y.M.,Lee, J.H.,Oh, T.-J. (deposition date: 2021-04-21, release date: 2021-07-14, Last modification date: 2023-11-29)

• Primary citation: Kim, K.H.,Lee, C.W.,Pardhe, B.D.,Hwang, J.,Do, H.,Lee, Y.M.,Lee, J.H.,Oh, T.J.; Crystal structure of an apo 7 alpha-hydroxysteroid dehydrogenase reveals key structural changes induced by substrate and co-factor binding.; J.Steroid Biochem.Mol.Biol., 212:105945-105945, 2021; PubMed: 34171491; DOI: 10.1016/j.jsbmb.2021.105945

Experimental method

X-RAY DIFFRACTION (2.703 Å)