7EKH

Structure of SARS-CoV-2 spike receptor-binding domain Y453F mutation complexed with human ACE2

7EKH の概要

• エントリーDOI: 10.2210/pdb7ekh/pdb
• 分子名称: Angiotensin-converting enzyme 2, Spike protein S1, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: sars-cov-2, spike, rbd, y453f, ace2, viral protein, hydrolase-viral protein complex, hydrolase/viral protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 96868.02

構造登録者

Han, P.C.,Su, C.,Zhang, Y.F.,Qi, J.X.,Gao, G.F. (登録日: 2021-04-05, 公開日: 2021-11-03, 最終更新日: 2023-11-29)

• 主引用文献: Han, P.,Su, C.,Zhang, Y.,Bai, C.,Zheng, A.,Qiao, C.,Wang, Q.,Niu, S.,Chen, Q.,Zhang, Y.,Li, W.,Liao, H.,Li, J.,Zhang, Z.,Cho, H.,Yang, M.,Rong, X.,Hu, Y.,Huang, N.,Yan, J.,Wang, Q.,Zhao, X.,Gao, G.F.,Qi, J.; Molecular insights into receptor binding of recent emerging SARS-CoV-2 variants.; Nat Commun, 12:6103-6103, 2021; PubMed: 34671049; DOI: 10.1038/s41467-021-26401-w

実験手法

X-RAY DIFFRACTION (2.4 Å)