7EJI

Crystal structure of KRED F147L/L153Q/Y190P/L199A/M205F/M206F variant and methyl methacrylate complex

Summary for 7EJI

• Entry DOI: 10.2210/pdb7eji/pdb
• Descriptor: 3-alpha-(Or 20-beta)-hydroxysteroid dehydrogenase, MAGNESIUM ION, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (10 entities in total)
• Functional Keywords: ketoreductases, nadph-dependent, enantioselectivity, oxidoreductase
• Biological source: Lactobacillus kefiri
• Total number of polymer chains: 4
• Total formula weight: 111628.46

Authors

Cui, J.,Huang, X.,Wang, B.,Zhao, H.,Zhou, J. (deposition date: 2021-04-02, release date: 2022-05-11, Last modification date: 2023-11-29)

• Primary citation: Huang, X.,Feng, J.,Cui, J.,Jiang, G.,Harrison, W.,Zang, X.,Zhou, J.,Wang, B.,Zhao, H.; Photoinduced chemomimetic biocatalysis for enantioselective intermolecular radical conjugate addition; Nat Catal, 2022; DOI: 10.1038/s41929-022-00777-4

Experimental method

X-RAY DIFFRACTION (1.56001602495 Å)