7EEU
Human p53 core domain with hot spot mutation R282W in complex with the natural CDKN1A(p21) p53-response element and Arsenic
Summary for 7EEU
Entry DOI | 10.2210/pdb7eeu/pdb |
Descriptor | Cellular tumor antigen p53, CDKN1A(p21) sense strand, CDKN1A(p21) anti-sense strand, ... (7 entities in total) |
Functional Keywords | dna-binding domain, complex, dna-bound, arsenic-bound, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 218507.44 |
Authors | Xing, Y.F.,Lu, M. (deposition date: 2021-03-19, release date: 2022-06-22, Last modification date: 2023-11-29) |
Primary citation | Xing, Y.F.,Lu, M. Human p53 core domain with hot spot mutation R282W in complex with the natural CDKN1A(p21) p53-response element and Arsenic To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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