7EDP

Crystal structure of AF10-DOT1L complex

Summary for 7EDP

• Entry DOI: 10.2210/pdb7edp/pdb
• Descriptor: Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein AF-10 (3 entities in total)
• Functional Keywords: complex, protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 9723.36

Authors

Chen, S.,Zhou, Z. (deposition date: 2021-03-16, release date: 2021-04-28, Last modification date: 2023-11-29)

• Primary citation: Zhou, Z.,Kang, S.,Huang, Z.,Zhou, Z.,Chen, S.; Structural characteristics of coiled-coil regions in AF10-DOT1L and AF10-inhibitory peptide complex.; J Leukoc Biol, 110:1091-1099, 2021; PubMed: 33993518; DOI: 10.1002/JLB.1MA0421-010R

Experimental method

X-RAY DIFFRACTION (2.2 Å)