7EB5
Cryo-EM structure of SARS-CoV-2 Spike D614G variant, two RBD-up conformation 2
Summary for 7EB5
Entry DOI | 10.2210/pdb7eb5/pdb |
Related | 7EAZ 7EB0 7EB3 7EB4 |
EMDB information | 31047 31048 31050 31051 31052 |
Descriptor | Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | sars-cov-2, spike protein, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) |
Total number of polymer chains | 3 |
Total formula weight | 442417.88 |
Authors | Yang, T.J.,Yu, P.Y.,Chang, Y.C.,Hsu, S.T.D. (deposition date: 2021-03-08, release date: 2021-06-23, Last modification date: 2022-01-05) |
Primary citation | Yang, T.J.,Yu, P.Y.,Chang, Y.C.,Hsu, S.D. D614G mutation in the SARS-CoV-2 spike protein enhances viral fitness by desensitizing it to temperature-dependent denaturation. J.Biol.Chem., 297:101238-101238, 2021 Cited by PubMed: 34563540DOI: 10.1016/j.jbc.2021.101238 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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