7E4B

Crystal structure of MIF bound to compound 5

Summary for 7E4B

• Entry DOI: 10.2210/pdb7e4b/pdb
• Descriptor: Macrophage migration inhibitory factor, CHLORIDE ION, 2-[2,4-bis(oxidanyl)phenyl]-3,5,7-tris(oxidanyl)chromen-4-one, ... (4 entities in total)
• Functional Keywords: tautomerase, cytokine, isomerase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 37509.22

Authors

Fan, C.P.,Guo, D.Y.,Yang, L. (deposition date: 2021-02-11, release date: 2023-02-15, Last modification date: 2023-11-29)

• Primary citation: Yang, L.,Guo, D.,Fan, C.; Identification and Structure-Activity Relationships of Dietary Flavonoids as Human Macrophage Migration Inhibitory Factor (MIF) Inhibitors.; J.Agric.Food Chem., 69:10138-10150, 2021; PubMed: 34459191; DOI: 10.1021/acs.jafc.1c03367

Experimental method

X-RAY DIFFRACTION (1.772 Å)