7E3H
Crystal structure of human acetylcholinesterase in complex with donepezil
Summary for 7E3H
Entry DOI | 10.2210/pdb7e3h/pdb |
Descriptor | Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE, ... (4 entities in total) |
Functional Keywords | human acetylcholinesterase, hache, alzheimer's disease, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 120365.79 |
Authors | Dileep, K.V.,Ihara, K.,Mishima-Tsumagari, C.,Kukimoto-Niino, M.,Yonemochi, M.,Hanada, K.,Shirouzu, M.,Zhang, K.Y.J. (deposition date: 2021-02-08, release date: 2022-02-16, Last modification date: 2023-11-29) |
Primary citation | Dileep, K.,Ihara, K.,Mishima-Tsumagari, C.,Kukimoto-Niino, M.,Yonemochi, M.,Hanada, K.,Shirouzu, M.,Zhang, K.Y. Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery Int.J.Biol.Macromol., 210:172-181, 2022 Cited by DOI: 10.1016/j.ijbiomac.2022.05.009PDB entries with the same primary citation |
Experimental method |
Structure validation
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