7DXF
Structure of BTDM-bound human TRPC6 nanodisc at 2.9 angstrom in high calcium state
Summary for 7DXF
Entry DOI | 10.2210/pdb7dxf/pdb |
EMDB information | 30907 6856 |
Descriptor | Short transient receptor potential channel 6, ZINC ION, [2-(1,3-benzodioxol-5-ylamino)-1,3-thiazol-4-yl]-[(3R,5S)-3,5-dimethylpiperidin-1-yl]methanone, ... (7 entities in total) |
Functional Keywords | trpc6, trpc, calcium, btdm, fsgs, channel, membrane protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 439358.27 |
Authors | |
Primary citation | Guo, W.,Tang, Q.,Wei, M.,Kang, Y.,Wu, J.X.,Chen, L. Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites. Neuron, 110:1023-1035.e5, 2022 Cited by PubMed: 35051376DOI: 10.1016/j.neuron.2021.12.023 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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