7DXD

Structure of TRPC3 at 3.9 angstrom in 1340 nM free calcium state

Summary for 7DXD

• Entry DOI: 10.2210/pdb7dxd/pdb
• EMDB information: 30905 6911
• Descriptor: Short transient receptor potential channel 3, CHOLESTEROL HEMISUCCINATE, ZINC ION, ... (4 entities in total)
• Functional Keywords: trpc3, trpc, calcium, channel, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 386841.76

Authors

Chen, L.,Guo, W. (deposition date: 2021-01-18, release date: 2022-01-19, Last modification date: 2022-08-17)

• Primary citation: Guo, W.,Tang, Q.,Wei, M.,Kang, Y.,Wu, J.X.,Chen, L.; Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.; Neuron, 110:1023-1035.e5, 2022; PubMed: 35051376; DOI: 10.1016/j.neuron.2021.12.023

Experimental method

ELECTRON MICROSCOPY (3.9 Å)