Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7DXD

Structure of TRPC3 at 3.9 angstrom in 1340 nM free calcium state

Functional Information from GO Data
ChainGOidnamespacecontents
A0005216molecular_functionmonoatomic ion channel activity
A0005227molecular_functioncalcium-activated cation channel activity
A0005262molecular_functioncalcium channel activity
A0005515molecular_functionprotein binding
A0005886cellular_componentplasma membrane
A0006811biological_processmonoatomic ion transport
A0006816biological_processcalcium ion transport
A0007338biological_processsingle fertilization
A0007602biological_processphototransduction
A0010524biological_processpositive regulation of calcium ion transport into cytosol
A0015279molecular_functionstore-operated calcium channel activity
A0016020cellular_componentmembrane
A0033198biological_processresponse to ATP
A0034220biological_processmonoatomic ion transmembrane transport
A0034703cellular_componentcation channel complex
A0046872molecular_functionmetal ion binding
A0051480biological_processregulation of cytosolic calcium ion concentration
A0051592biological_processresponse to calcium ion
A0055085biological_processtransmembrane transport
A0070588biological_processcalcium ion transmembrane transport
A0070679molecular_functioninositol 1,4,5 trisphosphate binding
A1903244biological_processpositive regulation of cardiac muscle hypertrophy in response to stress
B0005216molecular_functionmonoatomic ion channel activity
B0005227molecular_functioncalcium-activated cation channel activity
B0005262molecular_functioncalcium channel activity
B0005515molecular_functionprotein binding
B0005886cellular_componentplasma membrane
B0006811biological_processmonoatomic ion transport
B0006816biological_processcalcium ion transport
B0007338biological_processsingle fertilization
B0007602biological_processphototransduction
B0010524biological_processpositive regulation of calcium ion transport into cytosol
B0015279molecular_functionstore-operated calcium channel activity
B0016020cellular_componentmembrane
B0033198biological_processresponse to ATP
B0034220biological_processmonoatomic ion transmembrane transport
B0034703cellular_componentcation channel complex
B0046872molecular_functionmetal ion binding
B0051480biological_processregulation of cytosolic calcium ion concentration
B0051592biological_processresponse to calcium ion
B0055085biological_processtransmembrane transport
B0070588biological_processcalcium ion transmembrane transport
B0070679molecular_functioninositol 1,4,5 trisphosphate binding
B1903244biological_processpositive regulation of cardiac muscle hypertrophy in response to stress
C0005216molecular_functionmonoatomic ion channel activity
C0005227molecular_functioncalcium-activated cation channel activity
C0005262molecular_functioncalcium channel activity
C0005515molecular_functionprotein binding
C0005886cellular_componentplasma membrane
C0006811biological_processmonoatomic ion transport
C0006816biological_processcalcium ion transport
C0007338biological_processsingle fertilization
C0007602biological_processphototransduction
C0010524biological_processpositive regulation of calcium ion transport into cytosol
C0015279molecular_functionstore-operated calcium channel activity
C0016020cellular_componentmembrane
C0033198biological_processresponse to ATP
C0034220biological_processmonoatomic ion transmembrane transport
C0034703cellular_componentcation channel complex
C0046872molecular_functionmetal ion binding
C0051480biological_processregulation of cytosolic calcium ion concentration
C0051592biological_processresponse to calcium ion
C0055085biological_processtransmembrane transport
C0070588biological_processcalcium ion transmembrane transport
C0070679molecular_functioninositol 1,4,5 trisphosphate binding
C1903244biological_processpositive regulation of cardiac muscle hypertrophy in response to stress
D0005216molecular_functionmonoatomic ion channel activity
D0005227molecular_functioncalcium-activated cation channel activity
D0005262molecular_functioncalcium channel activity
D0005515molecular_functionprotein binding
D0005886cellular_componentplasma membrane
D0006811biological_processmonoatomic ion transport
D0006816biological_processcalcium ion transport
D0007338biological_processsingle fertilization
D0007602biological_processphototransduction
D0010524biological_processpositive regulation of calcium ion transport into cytosol
D0015279molecular_functionstore-operated calcium channel activity
D0016020cellular_componentmembrane
D0033198biological_processresponse to ATP
D0034220biological_processmonoatomic ion transmembrane transport
D0034703cellular_componentcation channel complex
D0046872molecular_functionmetal ion binding
D0051480biological_processregulation of cytosolic calcium ion concentration
D0051592biological_processresponse to calcium ion
D0055085biological_processtransmembrane transport
D0070588biological_processcalcium ion transmembrane transport
D0070679molecular_functioninositol 1,4,5 trisphosphate binding
D1903244biological_processpositive regulation of cardiac muscle hypertrophy in response to stress
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues508
DetailsTransmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"29726814","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues448
DetailsTopological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"29726814","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues120
DetailsTopological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"29726814","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues116
DetailsRepeat: {"description":"ANK 1","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues116
DetailsRepeat: {"description":"ANK 2","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues104
DetailsRepeat: {"description":"ANK 3","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues116
DetailsRepeat: {"description":"ANK 4","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues116
DetailsRepeat: {"description":"ANK 5","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues80
DetailsRegion: {"description":"Binds to IP3R3"}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues8
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"35051376","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DXB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7DXD","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues24
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"35051376","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DXB","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues4
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"29726814","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9535843","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6CUD","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

240971

PDB entries from 2025-08-27

PDB statisticsPDBj update infoContact PDBjnumon