7DUY

Crystal structure of VIM-2 MBL in complex with 1-(2-(1H-1,2,3-triazol-1-yl)ethyl)-1H-imidazole-2-carboxylic acid

Summary for 7DUY

Entry DOI	10.2210/pdb7duy/pdb
Descriptor	Beta-lactamase class B VIM-2, ZINC ION, 1-[2-(1,2,3-triazol-1-yl)ethyl]imidazole-2-carboxylic acid, ... (4 entities in total)
Functional Keywords	metallo-beta-lactamase vim-2, vim-2, hydrolase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	1
Total formula weight	25017.45
Authors	Li, G.-B.,Yan, Y.-H. (deposition date: 2021-01-12, release date: 2022-01-19, Last modification date: 2023-11-29)
Primary citation	Yan, Y.H.,Li, W.,Chen, W.,Li, C.,Zhu, K.R.,Deng, J.,Dai, Q.Q.,Yang, L.L.,Wang, Z.,Li, G.B. Structure-guided optimization of 1H-imidazole-2-carboxylic acid derivatives affording potent VIM-Type metallo-beta-lactamase inhibitors. Eur.J.Med.Chem., 228:113965-113965, 2022 Cited by PubMed: 34763944 DOI: 10.1016/j.ejmech.2021.113965 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.999 Å)

Structure validation