7DU9
Crystal structure of human Proto-oncogene tyrosine-protein kinase receptor Ret in complex with Pralsetinib
Summary for 7DU9
Entry DOI | 10.2210/pdb7du9/pdb |
Descriptor | Proto-oncogene tyrosine-protein kinase receptor Ret, Pralsetinib (3 entities in total) |
Functional Keywords | tyrosine-protein kinase, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 72483.67 |
Authors | Miyazaki, I.,Ishida, K.,Suzuki, T. (deposition date: 2021-01-08, release date: 2022-01-12, Last modification date: 2024-05-29) |
Primary citation | Miyazaki, I.,Ishida, K.,Suzuki, T. Selective RET inhibitor TAS0953/HM06 To be published, |
Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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