7DTW
Human Calcium-Sensing Receptor in the inactive close-close conformation
Summary for 7DTW
Entry DOI | 10.2210/pdb7dtw/pdb |
Related | 7DTT 7DTU 7DTV |
EMDB information | 30856 |
Descriptor | Extracellular calcium-sensing receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | gpcr, class c, calcium sensing receptor, membrane protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 250066.51 |
Authors | Ling, S.L.,Tian, C.L.,Shi, P.,Liu, S.L.,Meng, X.Y.,Liu, L.,Sun, D.M.,Shi, C.W. (deposition date: 2021-01-06, release date: 2021-03-10, Last modification date: 2021-04-14) |
Primary citation | Ling, S.,Shi, P.,Liu, S.,Meng, X.,Zhou, Y.,Sun, W.,Chang, S.,Zhang, X.,Zhang, L.,Shi, C.,Sun, D.,Liu, L.,Tian, C. Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca 2+ ions and L-tryptophan. Cell Res., 31:383-394, 2021 Cited by PubMed: 33603117DOI: 10.1038/s41422-021-00474-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.5 Å) |
Structure validation
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