7DTM
Crystal structure of metallo-beta-lactamase IMP-1 in complex with citrate.
Summary for 7DTM
Entry DOI | 10.2210/pdb7dtm/pdb |
Descriptor | Metallo-beta-lactamase type 2, ZINC ION, CITRATE ANION, ... (4 entities in total) |
Functional Keywords | metallo-beta-lactamase, zinc(ii) ion, citrate, hydrolase |
Biological source | Serratia marcescens |
Total number of polymer chains | 4 |
Total formula weight | 101866.38 |
Authors | Yamaguchi, Y.,Kurosaki, H. (deposition date: 2021-01-06, release date: 2021-08-04, Last modification date: 2023-11-29) |
Primary citation | Yamaguchi, Y.,Kato, K.,Ichimaru, Y.,Jin, W.,Sakai, M.,Abe, M.,Wachino, J.I.,Arakawa, Y.,Miyagi, Y.,Imai, M.,Fukuishi, N.,Yamagata, Y.,Otsuka, M.,Fujita, M.,Kurosaki, H. Crystal Structures of Metallo-beta-Lactamase (IMP-1) and Its D120E Mutant in Complexes with Citrate and the Inhibitory Effect of the Benzyl Group in Citrate Monobenzyl Ester. J.Med.Chem., 64:10019-10026, 2021 Cited by PubMed: 34242022DOI: 10.1021/acs.jmedchem.1c00308 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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