7DPJ

H-Ras Q61L in complex with GppNHp (state 1) after structural transition by humidity control

Summary for 7DPJ

• Entry DOI: 10.2210/pdb7dpj/pdb
• Related: 7DPH
• Descriptor: GTPase HRas, MAGNESIUM ION, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: oncoprotein, state transition, ras
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 19962.72

Authors

Taniguchi, H.,Matsumoto, S.,Miyamoto, R.,Kawamura, T.,Kumasaka, T.,Kataoka, T. (deposition date: 2020-12-19, release date: 2021-07-28, Last modification date: 2023-11-29)

• Primary citation: Matsumoto, S.,Taniguchi-Tamura, H.,Araki, M.,Kawamura, T.,Miyamoto, R.,Tsuda, C.,Shima, F.,Kumasaka, T.,Okuno, Y.,Kataoka, T.; Oncogenic mutations Q61L and Q61H confer active form-like structural features to the inactive state (state 1) conformation of H-Ras protein.; Biochem.Biophys.Res.Commun., 565:85-90, 2021; PubMed: 34102474; DOI: 10.1016/j.bbrc.2021.05.084

Experimental method

X-RAY DIFFRACTION (1.976 Å)