7DH5
Dog beta3 adrenergic receptor bound to mirabegron in complex with a miniGs heterotrimer
Summary for 7DH5
Entry DOI | 10.2210/pdb7dh5/pdb |
EMDB information | 30678 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | gpcr, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 133110.32 |
Authors | Shihoya, W.,Yamashita, K.,Nureki, O. (deposition date: 2020-11-12, release date: 2021-08-04, Last modification date: 2021-08-18) |
Primary citation | Nagiri, C.,Kobayashi, K.,Tomita, A.,Kato, M.,Kobayashi, K.,Yamashita, K.,Nishizawa, T.,Inoue, A.,Shihoya, W.,Nureki, O. Cryo-EM structure of the beta 3-adrenergic receptor reveals the molecular basis of subtype selectivity. Mol.Cell, 81:3205-3215.e5, 2021 Cited by PubMed: 34314699DOI: 10.1016/j.molcel.2021.06.024 PDB entries with the same primary citation |
Experimental method |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)