7DH5

Dog beta3 adrenergic receptor bound to mirabegron in complex with a miniGs heterotrimer

7DH5 の概要

• エントリーDOI: 10.2210/pdb7dh5/pdb
• EMDBエントリー: 30678
• 分子名称: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: gpcr, membrane protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 133110.32

構造登録者

Shihoya, W.,Yamashita, K.,Nureki, O. (登録日: 2020-11-12, 公開日: 2021-08-04, 最終更新日: 2021-08-18)

• 主引用文献: Nagiri, C.,Kobayashi, K.,Tomita, A.,Kato, M.,Kobayashi, K.,Yamashita, K.,Nishizawa, T.,Inoue, A.,Shihoya, W.,Nureki, O.; Cryo-EM structure of the beta 3-adrenergic receptor reveals the molecular basis of subtype selectivity.; Mol.Cell, 81:3205-3215.e5, 2021; PubMed: 34314699; DOI: 10.1016/j.molcel.2021.06.024

実験手法