7DFW

Cryo_EM structure of delta N-NPC1L1-CLR

7DFW の概要

• エントリーDOI: 10.2210/pdb7dfw/pdb
• EMDBエントリー: 30666
• 分子名称: NPC1-like intracellular cholesterol transporter 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: cholesterol, structural protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 148062.60

構造登録者

Hu, M.,Sun, S. (登録日: 2020-11-10, 公開日: 2021-08-11)

• 主引用文献: Hu, M.,Yang, F.,Huang, Y.,You, X.,Liu, D.,Sun, S.,Sui, S.F.; Structural insights into the mechanism of human NPC1L1-mediated cholesterol uptake.; Sci Adv, 7:-, 2021; PubMed: 34272236; DOI: 10.1126/sciadv.abg3188

実験手法

ELECTRON MICROSCOPY (2.69 Å)