7DDX

Crystal structure of KANK1 S1179F mutant in complex wtih eIF4A1

7DDX の概要

• エントリーDOI: 10.2210/pdb7ddx/pdb
• 分子名称: KN motif and ankyrin repeat domains 1, Eukaryotic initiation factor 4A-I, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: nephrotic syndrome, kidney ankyrin repeat-containing protein, eukaryotic initiation factor, complex, protein binding
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55147.86

構造登録者

Pan, W.,Xu, Y.,Wei, Z. (登録日: 2020-10-30, 公開日: 2021-09-08, 最終更新日: 2023-11-29)

• 主引用文献: Xu, Y.,Guo, C.,Pan, W.,Zhao, C.,Ding, Y.,Xie, X.,Wei, Z.,Sun, Y.,Yu, C.; Nephrotic-syndrome-associated mutation of KANK2 induces pathologic binding competition with physiological interactor KIF21A.; J.Biol.Chem., 297:100958-100958, 2021; PubMed: 34274317; DOI: 10.1016/j.jbc.2021.100958

実験手法

X-RAY DIFFRACTION (2.5 Å)