7D8E
Crystal Structure of double mutant Y115E Y117E human Secretory Glutaminyl Cyclase in complex with LSB-09
Summary for 7D8E
Entry DOI | 10.2210/pdb7d8e/pdb |
Descriptor | Glutaminyl-peptide cyclotransferase, ZINC ION, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | glutaminyl-peptide cyclotransferase, sqc, alzheimer's disease, pyroglutamate, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 114817.15 |
Authors | Dileep, K.V.,Ihara, K.,Sakai, N.,Shirozu, M.,Zhang, K.Y.J. (deposition date: 2020-10-08, release date: 2021-12-08, Last modification date: 2023-11-29) |
Primary citation | Dileep, K.V.,Ihara, K.,Sakai, N.,Shirozu, M.,Zhang, K.Y.J. Crystal Structure of double mutant Y115E Y117E human Secretory Glutaminyl Cyclase in complex with LSB-09 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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