7D7T

Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant bound to compound S43

Summary for 7D7T

Descriptorpapain-like protease, ZINC ION, N-[(3-acetamidophenyl)methyl]-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide (3 entities in total)
Functional Keywordsprotease, deubiquitinase, viral protein, hydrolase
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains2
Total molecular weight73211.78
Authors
Liu, J.,Wang, Y.,Xu, X.,Pan, L. (deposition date: 2020-10-05, release date: 2020-11-04)
Primary citation
Liu, J.,Wang, Y.,Pan, L.
Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant
To Be Published,
Experimental method
X-RAY DIFFRACTION (3.15 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.311170 1.8% 16.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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171916
PDB entries from 2020-12-02