7E35
Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant bound to compound S43
Replaces: 7D7TEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, A | Non-structural protein 3 | polymer | 315 | 35655.4 | 2 | UniProt (P0DTD1) Pfam (PF08715) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | Papain-like proteinase, nsp3, PL2-PRO, PL-PRO |
| 2 | B, A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | B, A | N-[(3-acetamidophenyl)methyl]-1-[(1R)-1-naphthalen-1-ylethyl]piperidine-4-carboxamide | non-polymer | 429.6 | 2 | Chemie (GYX) |
Sequence modifications
B, A: 2 - 316 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ser 112 | Cys 1674 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71310.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 989.9 | |
| All* | Total formula weight | 72300.8 |
