7D7L
The crystal structure of SARS-CoV-2 papain-like protease in complex with YM155
Summary for 7D7L
Entry DOI | 10.2210/pdb7d7l/pdb |
Descriptor | Non-structural protein 3, ZINC ION, CAFFEINE, ... (7 entities in total) |
Functional Keywords | protease, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
Total number of polymer chains | 2 |
Total formula weight | 73924.90 |
Authors | Zhao, Y.,Sun, L.,Yang, H.T.,Rao, Z.H. (deposition date: 2020-10-04, release date: 2021-04-21, Last modification date: 2021-11-17) |
Primary citation | Zhao, Y.,Du, X.,Duan, Y.,Pan, X.,Sun, Y.,You, T.,Han, L.,Jin, Z.,Shang, W.,Yu, J.,Guo, H.,Liu, Q.,Wu, Y.,Peng, C.,Wang, J.,Zhu, C.,Yang, X.,Yang, K.,Lei, Y.,Guddat, L.W.,Xu, W.,Xiao, G.,Sun, L.,Zhang, L.,Rao, Z.,Yang, H. High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors. Protein Cell, 12:877-888, 2021 Cited by PubMed: 33864621DOI: 10.1007/s13238-021-00836-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.11 Å) |
Structure validation
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