7D77

Cryo-EM structure of the cortisol-bound adhesion receptor GPR97-Go complex

7D77 の概要

• エントリーDOI: 10.2210/pdb7d77/pdb
• EMDBエントリー: 30603
• 分子名称: Guanine nucleotide-binding protein G(o) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (10 entities in total)
• 機能のキーワード: gpcr, gpr97, complex, adhesion g protein-coupled receptor, membrane protein
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 163163.34

構造登録者

Ping, Y.,Mao, C.,Xiao, P.,Zhao, R.,Jiang, Y.,Yang, Z.,An, W.,Shen, D.,Yang, F.,Zhang, H.,Qu, C.,Shen, Q.,Tian, C.,Li, Z.,Li, S.,Wang, G.,Tao, X.,Wen, X.,Zhong, Y.,Yang, J.,Yi, F.,Yu, X.,Xu, E.,Zhang, Y.,Sun, J. (登録日: 2020-10-03, 公開日: 2021-02-03, 最終更新日: 2021-02-10)

• 主引用文献: Ping, Y.Q.,Mao, C.,Xiao, P.,Zhao, R.J.,Jiang, Y.,Yang, Z.,An, W.T.,Shen, D.D.,Yang, F.,Zhang, H.,Qu, C.,Shen, Q.,Tian, C.,Li, Z.J.,Li, S.,Wang, G.Y.,Tao, X.,Wen, X.,Zhong, Y.N.,Yang, J.,Yi, F.,Yu, X.,Xu, H.E.,Zhang, Y.,Sun, J.P.; Structures of the glucocorticoid-bound adhesion receptor GPR97-G o complex.; Nature, 589:620-626, 2021; PubMed: 33408414; DOI: 10.1038/s41586-020-03083-w

実験手法

ELECTRON MICROSCOPY (2.9 Å)