7D77
Cryo-EM structure of the cortisol-bound adhesion receptor GPR97-Go complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Guanine nucleotide-binding protein G(o) subunit alpha | polymer | 226 | 25286.9 | 1 | Pfam (PF00503) UniProt (by SIFTS) (P09471) In PDB | Homo sapiens | |
2 | B | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 346 | 38245.8 | 1 | UniProt (P62873) Pfam (PF00400) In PDB | Homo sapiens (Human) | Transducin beta chain 1 |
3 | G | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 71 | 7861.1 | 1 | UniProt (P59768) Pfam (PF00631) In PDB | Homo sapiens (Human) | G gamma-I |
4 | R | Adhesion G protein-coupled receptor G3; GPR97 | polymer | 561 | 62767.1 | 1 | Pfam (PF01825) Pfam (PF00002) UniProt (by SIFTS) (Q86Y34) In PDB | Homo sapiens | |
5 | S | scFv16 | polymer | 250 | 26610.6 | 1 | synthetic construct | ||
6 | A, R | PALMITIC ACID | non-polymer | 256.4 | 3 | Chemie (PLM) | |||
7 | R | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) | |||
8 | R | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione | non-polymer | 362.5 | 1 | Chemie (HCY) | |||
9 | R | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) | |||
10 | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
B: 1 - 340 (UniProt: P62873)
PDB | External Database | Details |
---|---|---|
His 341 | - | expression tag |
His 342 | - | expression tag |
His 343 | - | expression tag |
His 344 | - | expression tag |
His 345 | - | expression tag |
His 346 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 160771.6 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 2391.8 | |
All* | Total formula weight | 163163.3 |