7D6Y

eIF4E in Complex with a Disulphide-Free Autonomous VH Domain

7D6Y の概要

• エントリーDOI: 10.2210/pdb7d6y/pdb
• 分子名称: Eukaryotic translation initiation factor 4E, VH Domain (1C5), [[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE, ... (5 entities in total)
• 機能のキーワード: vh domain, cap-dependent translation, rna binding protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43017.48

構造登録者

Brown, C.J.,Frosi, Y.,Jiang, S.,Lin, Y.C. (登録日: 2020-10-02, 公開日: 2021-10-06, 最終更新日: 2023-11-29)

• 主引用文献: Frosi, Y.,Lin, Y.C.,Jiang, S.,Ramlan, S.R.,Hew, K.,Asial, I.,Engman, A.H.,Goh, M.,Thean, D.,Nordlund, P.,Lane, D.P.,Brown, C.J.; Engineering Disulphide-Free Autonomous Antibody VH Domains to modulate intracellular pathways; To Be Published,

実験手法

X-RAY DIFFRACTION (1.668 Å)