7D4P

Structure of human TRPC5 in complex with clemizole

Summary for 7D4P

• Entry DOI: 10.2210/pdb7d4p/pdb
• EMDB information: 30575 9615
• Descriptor: Short transient receptor potential channel 5, 1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole, PHOSPHATIDYLETHANOLAMINE, ... (8 entities in total)
• Functional Keywords: clemizole, trpc5, trpc, metal transport
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 367422.76

Authors

Chen, L.,Song, K.,Wei, M.,Guo, W. (deposition date: 2020-09-24, release date: 2021-03-31, Last modification date: 2021-10-13)

• Primary citation: Song, K.,Wei, M.,Guo, W.,Quan, L.,Kang, Y.,Wu, J.X.,Chen, L.; Structural basis for human TRPC5 channel inhibition by two distinct inhibitors.; Elife, 10:-, 2021; PubMed: 33683200; DOI: 10.7554/eLife.63429

Experimental method

ELECTRON MICROSCOPY (2.7 Å)