7D4F
Structure of COVID-19 RNA-dependent RNA polymerase bound to suramin
Summary for 7D4F
Entry DOI | 10.2210/pdb7d4f/pdb |
EMDB information | 30572 |
Descriptor | Non-structural protein 8, Non-structural protein 7, RNA-directed RNA polymerase, ... (5 entities in total) |
Functional Keywords | covid-19, rna polymerase, suramin binding, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 4 |
Total formula weight | 162815.84 |
Authors | |
Primary citation | Yin, W.,Luan, X.,Li, Z.,Zhou, Z.,Wang, Q.,Gao, M.,Wang, X.,Zhou, F.,Shi, J.,You, E.,Liu, M.,Wang, Q.,Jiang, Y.,Jiang, H.,Xiao, G.,Zhang, L.,Yu, X.,Zhang, S.,Eric Xu, H. Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin. Nat.Struct.Mol.Biol., 28:319-325, 2021 Cited by PubMed: 33674802DOI: 10.1038/s41594-021-00570-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.57 Å) |
Structure validation
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