7D26
Hsp90 alpha N-terminal domain in complex with a 8 compund
Summary for 7D26
Entry DOI | 10.2210/pdb7d26/pdb |
Descriptor | Heat shock protein HSP 90-alpha, 6-chloranyl-9-[(2-phenyl-1,3-oxazol-5-yl)methyl]purin-2-amine (3 entities in total) |
Functional Keywords | chaperone-inhibitor complex, chaperone/inhibitor |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 1 |
Total formula weight | 24436.02 |
Authors | Shin, S.C.,Kim, E.E. (deposition date: 2020-09-15, release date: 2021-07-28, Last modification date: 2023-11-29) |
Primary citation | Shin, S.C.,El-Damasy, A.K.,Lee, J.H.,Seo, S.H.,Kim, J.H.,Seo, Y.H.,Lee, Y.,Yu, J.H.,Bang, E.K.,Kim, E.E.,Keum, G. Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90. Int J Mol Sci, 21:-, 2020 Cited by PubMed: 33317068DOI: 10.3390/ijms21249377 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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