7CZM
Crystal structure of FIP200 Claw/p-OPtineurin LIR complex
Summary for 7CZM
Entry DOI | 10.2210/pdb7czm/pdb |
Descriptor | RB1-inducible coiled-coil protein 1, Optineurin LIR, GLYCEROL, ... (5 entities in total) |
Functional Keywords | autophagy, fip200, optineurin, signaling protein, signaling protein-protein binding complex, signaling protein/protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 28293.85 |
Authors | Zhou, Z.X.,Pan, L.F. (deposition date: 2020-09-09, release date: 2021-03-31, Last modification date: 2023-11-29) |
Primary citation | Zhou, Z.,Liu, J.,Fu, T.,Wu, P.,Peng, C.,Gong, X.,Wang, Y.,Zhang, M.,Li, Y.,Wang, Y.,Xu, X.,Li, M.,Pan, L. Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation. Nat Commun, 12:1570-1570, 2021 Cited by PubMed: 33692357DOI: 10.1038/s41467-021-21874-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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