7CZ5

Cryo-EM structure of the human growth hormone-releasing hormone receptor-Gs protein complex

7CZ5 の概要

• エントリーDOI: 10.2210/pdb7cz5/pdb
• EMDBエントリー: 30505
• 分子名称: Growth hormone-releasing hormone receptor,growth hormone-releasing hormone receptor, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Somatoliberin, ... (9 entities in total)
• 機能のキーワード: cognate receptor, class b g-protein-coupled receptors, single particle, membrane protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 178562.25

構造登録者

Zhou, F.,Zhang, H.,Cong, Z.,Zhao, L.,Zhou, Q.,Mao, C.,Cheng, X.,Shen, D.,Cai, X.,Ma, C.,Wang, Y.,Dai, A.,Zhou, Y.,Sun, W.,Zhao, F.,Zhao, S.,Jiang, H.,Jiang, Y.,Yang, D.,Xu, H.E.,Zhang, Y.,Wang, M. (登録日: 2020-09-07, 公開日: 2020-11-18)

• 主引用文献: Zhou, F.,Zhang, H.,Cong, Z.,Zhao, L.H.,Zhou, Q.,Mao, C.,Cheng, X.,Shen, D.D.,Cai, X.,Ma, C.,Wang, Y.,Dai, A.,Zhou, Y.,Sun, W.,Zhao, F.,Zhao, S.,Jiang, H.,Jiang, Y.,Yang, D.,Eric Xu, H.,Zhang, Y.,Wang, M.W.; Structural basis for activation of the growth hormone-releasing hormone receptor.; Nat Commun, 11:5205-5205, 2020; PubMed: 33060564; DOI: 10.1038/s41467-020-18945-0

実験手法

ELECTRON MICROSCOPY (2.6 Å)