7CYL
Crystal structure of Karyopherin-beta2 in complex with FUS PY-NLS(P525L)
Summary for 7CYL
Entry DOI | 10.2210/pdb7cyl/pdb |
Descriptor | Transportin-1, RNA-binding protein FUS (2 entities in total) |
Functional Keywords | nuclear import, karyopherin, transport protein, transport protein-rna binding protein complex, transport protein/rna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 104113.59 |
Authors | Yoshizawa, T.,Chook, Y.M. (deposition date: 2020-09-03, release date: 2021-02-24, Last modification date: 2023-11-29) |
Primary citation | Gonzalez, A.,Mannen, T.,Cagatay, T.,Fujiwara, A.,Matsumura, H.,Niesman, A.B.,Brautigam, C.A.,Chook, Y.M.,Yoshizawa, T. Mechanism of karyopherin-beta 2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X). Sci Rep, 11:3754-3754, 2021 Cited by PubMed: 33580145DOI: 10.1038/s41598-021-83196-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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