7CYC

Cryo-EM structures of Alphacoronavirus spike glycoprotein

「6IXA」から置き換えられました

7CYC の概要

• エントリーDOI: 10.2210/pdb7cyc/pdb
• EMDBエントリー: 30496
• 分子名称: Spike glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: alphacoronavirus, spike glycoprotein, structural protein
• 由来する生物種: Human coronavirus 229E (HCoV-229E)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 386321.78

構造登録者

Song, X.,Shi, Y.,Ding, W.,Liu, Z.J.,Peng, G. (登録日: 2020-09-03, 公開日: 2020-12-23, 最終更新日: 2021-06-02)

• 主引用文献: Song, X.,Shi, Y.,Ding, W.,Niu, T.,Sun, L.,Tan, Y.,Chen, Y.,Shi, J.,Xiong, Q.,Huang, X.,Xiao, S.,Zhu, Y.,Cheng, C.,Fu, Z.F.,Liu, Z.J.,Peng, G.; Cryo-EM analysis of the HCoV-229E spike glycoprotein reveals dynamic prefusion conformational changes.; Nat Commun, 12:141-141, 2021; PubMed: 33420048; DOI: 10.1038/s41467-020-20401-y

実験手法

ELECTRON MICROSCOPY (3.21 Å)