7CXW

Structural insights into novel mechanisms of inhibition of the major b-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus (C116 flipped form)

Summary for 7CXW

• Entry DOI: 10.2210/pdb7cxw/pdb
• Descriptor: Carbonic anhydrase, ACETATE ION (3 entities in total)
• Functional Keywords: b-class carbonic anhydrase, zinc metalloenzyme, cafb, aspergillus fumigatus, oxidative inhibition, zinc-free inactivation, lyase
• Biological source: Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
• Total number of polymer chains: 2
• Total formula weight: 52299.39

Authors

Jin, M.S.,Kim, S.,Yeon, J.,Sung, J.,Kim, N.J.,Hong, S. (deposition date: 2020-09-02, release date: 2021-03-31, Last modification date: 2023-11-29)

• Primary citation: Kim, S.,Yeon, J.,Sung, J.,Kim, N.J.,Hong, S.,Jin, M.S.; Structural insights into novel mechanisms of inhibition of the major beta-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus.; J.Struct.Biol., 213:107700-107700, 2021; PubMed: 33545350; DOI: 10.1016/j.jsb.2021.107700

Experimental method

X-RAY DIFFRACTION (2.2 Å)