7CXB

Structure of mouse Galectin-3 CRD in complex with TD-139 belonging to P6522 space group.

7CXB の概要

• エントリーDOI: 10.2210/pdb7cxb/pdb
• 関連するPDBエントリー: 7CXA 7CXC 7CXD
• 分子名称: Galectin-3, 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: beta-galactose binding protein, carbohydrate, sugar binding protein
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 19323.33

構造登録者

Kumar, A. (登録日: 2020-09-01, 公開日: 2021-09-01, 最終更新日: 2023-11-29)

• 主引用文献: Kumar, A.,Paul, M.,Panda, M.,Jayaram, S.,Kalidindi, N.,Sale, H.,Vetrichelvan, M.,Gupta, A.,Mathur, A.,Beno, B.,Regueiro-Ren, A.,Cheng, D.,Ramarao, M.,Ghosh, K.; Molecular mechanism of interspecies differences in the binding affinity of TD139 to Galectin-3.; Glycobiology, 31:1390-1400, 2021; PubMed: 34228782; DOI: 10.1093/glycob/cwab072

実験手法

X-RAY DIFFRACTION (1.46 Å)