7CXB
Structure of mouse Galectin-3 CRD in complex with TD-139 belonging to P6522 space group.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Galectin-3 | polymer | 165 | 18639.2 | 1 | UniProt (P16110) Pfam (PF00337) | Mus musculus (Mouse) | Gal-3,35 kDa lectin,Carbohydrate-binding protein 35,CBP 35,Galactose-specific lectin 3,IgE-binding protein,L-34 galactoside-binding lectin,Laminin-binding protein,Lectin L-29,Mac-2 antigen |
| 2 | B (A) | 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside | non-polymer | 648.6 | 1 | Chemie (TD2) PubChem (73774610) PubChem (90109156) PubChem (118436792) PubChem (118679947) PubChem (118657353) PubChem (122418481) PubChem (126624445) PubChem (126624423) PubChem (130471368) PubChem (118404248) PubChem (118408645) PubChem (118507865) PubChem (134692124) PubChem (118680035) PubChem (126624426) PubChem (129261745) PubChem (140639477) PubChem (140820580) PubChem (145121529) PubChem (153447831) PubChem (173976503) PubChem (173733738) PubChem (173742413) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 4 | D (A) | water | water | 18.0 | 163 | Chemie (HOH) |
Sequence modifications
A: 122 - 264 (UniProt: P16110)
| PDB | External Database | Details |
|---|---|---|
| Met 100 | - | expression tag |
| Gly 101 | - | expression tag |
| Ser 102 | - | expression tag |
| Ser 103 | - | expression tag |
| His 104 | - | expression tag |
| His 105 | - | expression tag |
| His 106 | - | expression tag |
| His 107 | - | expression tag |
| His 108 | - | expression tag |
| His 109 | - | expression tag |
| Ser 110 | - | expression tag |
| Ser 111 | - | expression tag |
| Gly 112 | - | expression tag |
| Glu 113 | - | expression tag |
| Thr 114 | - | expression tag |
| Val 115 | - | expression tag |
| Arg 116 | - | expression tag |
| Phe 117 | - | expression tag |
| Gln 118 | - | expression tag |
| Gly 119 | - | expression tag |
| His 120 | - | expression tag |
| Met 121 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18639.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 684.1 | |
| All* | Total formula weight | 19323.3 |
