7CT5

S protein of SARS-CoV-2 in complex bound with T-ACE2

7CT5 の概要

• エントリーDOI: 10.2210/pdb7ct5/pdb
• EMDBエントリー: 30460 30461
• 分子名称: Spike glycoprotein, Angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: s-ecd, ace2, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 674913.50

構造登録者

Guo, L.,Bi, W.W.,Zhang, Y.Y.,Yan, R.H.,Li, Y.N.,Zhou, Q.,Dang, B.B. (登録日: 2020-08-18, 公開日: 2020-11-18, 最終更新日: 2021-02-10)

• 主引用文献: Guo, L.,Bi, W.,Wang, X.,Xu, W.,Yan, R.,Zhang, Y.,Zhao, K.,Li, Y.,Zhang, M.,Cai, X.,Jiang, S.,Xie, Y.,Zhou, Q.,Lu, L.,Dang, B.; Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection.; Cell Res., 31:98-100, 2021; PubMed: 33177651; DOI: 10.1038/s41422-020-00438-w

実験手法

ELECTRON MICROSCOPY (4 Å)