7CQT

Crystal structure of Brassica juncea HMG-CoA synthase 1 mutant - S359A in complex with acetyl-CoA

Summary for 7CQT

Entry DOI	10.2210/pdb7cqt/pdb
Descriptor	3-hydroxy-3-methylglutaryl coenzyme A synthase, ACETYL COENZYME *A, ADENOSINE-3'-5'-DIPHOSPHATE (3 entities in total)
Functional Keywords	hmgs, s359a, mevalonate pathway, acetyl-coa, biosynthetic protein, transferase
Biological source	Brassica juncea (Indian mustard)
Total number of polymer chains	4
Total formula weight	206430.10
Authors	Liao, P.,Hu, M.,Kong, G.K.W.,Hao, Q.,Chye, M.L. (deposition date: 2020-08-11, release date: 2021-07-14, Last modification date: 2023-11-29)
Primary citation	Liao, P.,Lung, S.C.,Chan, W.L.,Hu, M.,Kong, G.K.,Bach, T.J.,Hao, Q.,Lo, C.,Chye, M.L. Overexpression and Inhibition of 3-Hydroxy-3-Methylglutaryl-CoA Synthase Affect Central Metabolic Pathways in Tobacco. Plant Cell.Physiol., 62:205-218, 2021 Cited by PubMed: 33340324 DOI: 10.1093/pcp/pcaa154 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation