7CQT

Crystal structure of Brassica juncea HMG-CoA synthase 1 mutant - S359A in complex with acetyl-CoA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004421	molecular_function	hydroxymethylglutaryl-CoA synthase activity
A	0006084	biological_process	acetyl-CoA metabolic process
A	0006696	biological_process	ergosterol biosynthetic process
A	0008299	biological_process	isoprenoid biosynthetic process
A	0010142	biological_process	farnesyl diphosphate biosynthetic process, mevalonate pathway
A	0016126	biological_process	sterol biosynthetic process
A	0016740	molecular_function	transferase activity
A	0042802	molecular_function	identical protein binding
B	0004421	molecular_function	hydroxymethylglutaryl-CoA synthase activity
B	0006084	biological_process	acetyl-CoA metabolic process
B	0006696	biological_process	ergosterol biosynthetic process
B	0008299	biological_process	isoprenoid biosynthetic process
B	0010142	biological_process	farnesyl diphosphate biosynthetic process, mevalonate pathway
B	0016126	biological_process	sterol biosynthetic process
B	0016740	molecular_function	transferase activity
B	0042802	molecular_function	identical protein binding
C	0004421	molecular_function	hydroxymethylglutaryl-CoA synthase activity
C	0006084	biological_process	acetyl-CoA metabolic process
C	0006696	biological_process	ergosterol biosynthetic process
C	0008299	biological_process	isoprenoid biosynthetic process
C	0010142	biological_process	farnesyl diphosphate biosynthetic process, mevalonate pathway
C	0016126	biological_process	sterol biosynthetic process
C	0016740	molecular_function	transferase activity
C	0042802	molecular_function	identical protein binding
D	0004421	molecular_function	hydroxymethylglutaryl-CoA synthase activity
D	0006084	biological_process	acetyl-CoA metabolic process
D	0006696	biological_process	ergosterol biosynthetic process
D	0008299	biological_process	isoprenoid biosynthetic process
D	0010142	biological_process	farnesyl diphosphate biosynthetic process, mevalonate pathway
D	0016126	biological_process	sterol biosynthetic process
D	0016740	molecular_function	transferase activity
D	0042802	molecular_function	identical protein binding

Functional Information from PROSITE/UniProt

site_id	PS01226
Number of Residues	16
Details	HMG_COA_SYNTHASE Hydroxymethylglutaryl-coenzyme A synthase active site. NtDVEGVDstNACYgG

Chain	Residue	Details
A	ASN105-GLY120

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