7CP1

Crystal structure of isocitrate lyase in complex with succinate and itaconate

7CP1 の概要

• エントリーDOI: 10.2210/pdb7cp1/pdb
• 分子名称: Isocitrate lyase, SUCCINIC ACID, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: glyoxylate cycle, isocitrate lyase, succinate, itaconate, mycobacterium tuberculosis, lyase
• 由来する生物種: Mycobacterium tuberculosis H37Rv
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 96707.86

構造登録者

Kwon, S.,Park, H.H. (登録日: 2020-08-05, 公開日: 2021-05-19, 最終更新日: 2023-11-29)

• 主引用文献: Kwon, S.,Chun, H.L.,Ha, H.J.,Lee, S.Y.,Park, H.H.; Heterogeneous multimeric structure of isocitrate lyase in complex with succinate and itaconate provides novel insights into its inhibitory mechanism.; Plos One, 16:e0251067-e0251067, 2021; PubMed: 33951112; DOI: 10.1371/journal.pone.0251067

実験手法

X-RAY DIFFRACTION (2.58 Å)