7CLI

Structure of NF-kB p52 homodimer bound to P-Selectin kB DNA fragment

Summary for 7CLI

• Entry DOI: 10.2210/pdb7cli/pdb
• Descriptor: Nuclear factor NF-kappa-B p52 subunit, DNA (5'-D(*CP*AP*AP*GP*GP*GP*GP*TP*CP*AP*CP*CP*CP*CP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*GP*GP*GP*GP*TP*GP*AP*CP*CP*CP*CP*TP*TP*G)-3'), ... (4 entities in total)
• Functional Keywords: dna-protein complex, transcription factor, transcription, dna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 98500.13

Authors

Meshcheryakov, V.A.,Wang, V.Y.-F. (deposition date: 2020-07-21, release date: 2021-07-21, Last modification date: 2023-11-29)

• Primary citation: Pan, W.,Meshcheryakov, V.A.,Li, T.,Wang, Y.,Ghosh, G.,Wang, V.Y.; Structures of NF-kappa B p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation.; Elife, 12:-, 2023; PubMed: 36779700; DOI: 10.7554/eLife.86258

Experimental method

X-RAY DIFFRACTION (3 Å)