7CKW
Cryo-EM structure of Fenoldopam bound dopamine receptor DRD1-Gs signaling complex
Summary for 7CKW
Entry DOI | 10.2210/pdb7ckw/pdb |
EMDB information | 30392 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | transmembrane protein, signaling transduction, cell cycle |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 160553.94 |
Authors | |
Primary citation | Xiao, P.,Yan, W.,Gou, L.,Zhong, Y.N.,Kong, L.,Wu, C.,Wen, X.,Yuan, Y.,Cao, S.,Qu, C.,Yang, X.,Yang, C.C.,Xia, A.,Hu, Z.,Zhang, Q.,He, Y.H.,Zhang, D.L.,Zhang, C.,Hou, G.H.,Liu, H.,Zhu, L.,Fu, P.,Yang, S.,Rosenbaum, D.M.,Sun, J.P.,Du, Y.,Zhang, L.,Yu, X.,Shao, Z. Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes. Cell, 184:943-956.e18, 2021 Cited by PubMed: 33571432DOI: 10.1016/j.cell.2021.01.028 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.22 Å) |
Structure validation
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