7CJF

Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody Fab

Summary for 7CJF

• Entry DOI: 10.2210/pdb7cjf/pdb
• Descriptor: antibody heavy chain, antibody light chain, Spike protein S1, ... (5 entities in total)
• Functional Keywords: sars-cov-2, rbd, antibody, viral protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 69546.63

Authors

Guo, Y.,Li, X.,Zhang, G.,Fu, D.,Schweizer, L.,Zhang, H.,Rao, Z. (deposition date: 2020-07-10, release date: 2020-11-11, Last modification date: 2023-11-29)

• Primary citation: Guo, Y.,Huang, L.,Zhang, G.,Yao, Y.,Zhou, H.,Shen, S.,Shen, B.,Li, B.,Li, X.,Zhang, Q.,Chen, M.,Chen, D.,Wu, J.,Fu, D.,Zeng, X.,Feng, M.,Pi, C.,Wang, Y.,Zhou, X.,Lu, M.,Li, Y.,Fang, Y.,Lu, Y.Y.,Hu, X.,Wang, S.,Zhang, W.,Gao, G.,Adrian, F.,Wang, Q.,Yu, F.,Peng, Y.,Gabibov, A.G.,Min, J.,Wang, Y.,Huang, H.,Stepanov, A.,Zhang, W.,Cai, Y.,Liu, J.,Yuan, Z.,Zhang, C.,Lou, Z.,Deng, F.,Zhang, H.,Shan, C.,Schweizer, L.,Sun, K.,Rao, Z.; A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes.; Nat Commun, 12:2623-2623, 2021; PubMed: 33976198; DOI: 10.1038/s41467-021-22926-2

Experimental method

X-RAY DIFFRACTION (2.108 Å)