7CIN

Crystal structure of the extended-spectrum class C beta-lactamase AmpC BER with the ordered R2 loop

Summary for 7CIN

• Entry DOI: 10.2210/pdb7cin/pdb
• Related: 5gzw 5joc
• Descriptor: Beta-lactamase, SULFATE ION (3 entities in total)
• Functional Keywords: class c beta-lactamase, wild-type ampc ber, two amino acid insertion in the r2 loop, ordered r2 loop, hydrolase
• Biological source: Escherichia coli K-12
• Total number of polymer chains: 2
• Total formula weight: 81400.25

Authors

Jeong, B.G.,Cha, S.S. (deposition date: 2020-07-07, release date: 2021-05-19, Last modification date: 2023-11-29)

• Primary citation: Jeong, B.G.,Na, J.H.,Bae, D.W.,Park, S.B.,Lee, H.S.,Cha, S.S.; Crystal structure of AmpC BER and molecular docking lead to the discovery of broad inhibition activities of halisulfates against beta-lactamases.; Comput Struct Biotechnol J, 19:145-152, 2021; PubMed: 33425247; DOI: 10.1016/j.csbj.2020.12.015

Experimental method

X-RAY DIFFRACTION (1.79006366468 Å)