7CHV

Metallo-Beta-Lactamase VIM-2 in complex with 1-benzyl-1H-imidazole-2-carboxylic acid

Summary for 7CHV

Entry DOI	10.2210/pdb7chv/pdb
Descriptor	Beta-lactamase class B VIM-2, ZINC ION, 1-(phenylmethyl)imidazole-2-carboxylic acid, ... (5 entities in total)
Functional Keywords	metallo-beta-lactamase vim-2, vim-2, hydrolase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	1
Total formula weight	25169.92
Authors	Yan, Y.-H.,Li, G.-B. (deposition date: 2020-07-06, release date: 2021-07-14, Last modification date: 2023-11-29)
Primary citation	Dai, Q.,Yan, Y.,Ning, X.,Li, G.,Yu, J.,Deng, J.,Yang, L.,Li, G.B. AncPhore: A versatile tool for anchor pharmacophore steered drug discovery with applications in discovery of new inhibitors targeting metallo-beta-lactamases and indoleamine/tryptophan 2,3-dioxygenases. Acta Pharm Sin B, 11:1931-1946, 2021 Cited by PubMed: 34386329 DOI: 10.1016/j.apsb.2021.01.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.174 Å)

Structure validation