7CET
Crystal structure of D-cycloserine-bound form of cysteine desulfurase NifS from Helicobacter pylori
Summary for 7CET
Entry DOI | 10.2210/pdb7cet/pdb |
Descriptor | Cysteine desulfurase IscS, ISOPROPYL ALCOHOL, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | cysteine desulfurase, plp-dependent enzyme, cysteine metabolism, cycloserine, inhibitor, fe-s cluster biosynthesis, biosynthetic protein |
Biological source | Helicobacter pylori 26695 |
Total number of polymer chains | 1 |
Total formula weight | 44552.00 |
Authors | Nakamura, R.,Takahashi, Y.,Fujishiro, T. (deposition date: 2020-06-24, release date: 2021-06-30, Last modification date: 2023-11-29) |
Primary citation | Nakamura, R.,Ogawa, S.,Takahashi, Y.,Fujishiro, T. Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022 Cited by PubMed: 35395703DOI: 10.1111/febs.16455 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.64 Å) |
Structure validation
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